GLI1（12q13）基因探針

 廣州健侖生物科技?有限公司 

本司長期供應(yīng)尼古?。商鎸帲z測試劑盒，其主要品牌包括美國NovaBios、廣州健侖、廣州創(chuàng)侖等進(jìn)口產(chǎn)品，國產(chǎn)產(chǎn)品，試劑盒的實(shí)驗(yàn)方法是膠體金方法。

我司還有很多熒光原位雜交系列檢測試劑盒以及各種FISH基因探針和染色體探針等，。

GLI1（12q13）基因探針

   本試劑盒主要用于GLI1（12q13）基因的檢測，里面包括即用型雜交液和DAPI復(fù)染劑。
本試劑盒僅供科研使用。

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二維碼掃一掃

【公司名稱】 廣州健侖生物科技有限公司
【】    楊永漢 

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【騰訊 】
【公司地址】 廣州清華科技園創(chuàng)新基地番禺石樓鎮(zhèn)創(chuàng)啟路63號二期2幢101-3室

【企業(yè)文化宣傳】

在中國殘疾人聯(lián)合會(huì)發(fā)布的《關(guān)于開展第19次全國“愛耳日”宣傳教育活動(dòng)的通知》中所列明的工作項(xiàng)目中，便提到了“開展耳聾基因篩查”“預(yù)防和減少藥物導(dǎo)致聽力殘疾的發(fā)生”。

在趙亮看來，基因檢測對于預(yù)防藥物性耳聾作用重大，他介紹說：“一部分藥物性耳聾會(huì)和遺傳基因有關(guān)，對于經(jīng)耳聾基因檢測中發(fā)現(xiàn)有線粒體基因突變的孩子，其對耳毒性藥物的敏感性要超過普通孩子，更應(yīng)該嚴(yán)格控制用藥。”

對于耳聾基因篩查，冀連梅表示，目前國內(nèi)已廣泛存在針對新生兒耳聾基因攜帶者的專業(yè)篩查，以確定新生兒是否有氨基糖甙類致聾基因。

她轉(zhuǎn)發(fā)給北京晨報(bào)記者一張患者曾出示過的基因篩查后的“用藥指南”卡片，卡片上標(biāo)明了這樣的文字：“您本人及母系家族成員應(yīng)終生禁用或慎用氨基糖甙類抗生素，然后列出了鏈霉素、卡那霉素等10多種抗生素的名字。”

冀連梅強(qiáng)調(diào)，基因篩查之后，醫(yī)生都會(huì)給新生兒家長一張這樣的卡片，上面注明了哪些藥物要禁用或慎用。家長在帶孩子看病時(shí)，即可將卡片出示給醫(yī)生。

耳毒性藥物仍未退出治療

基層藥師應(yīng)加強(qiáng)培訓(xùn)教育

盡管藥物性耳聾兒童人群龐大，不過冀連梅藥師指出，“過去認(rèn)為藥物使用不當(dāng)是造成兒童耳聾的主要原因之一，現(xiàn)在的大城市應(yīng)該不會(huì)存在這類問題了，但在基層，濫用藥物的現(xiàn)象還很普遍。”冀連梅透露，像慶大霉素如今的確仍在基層使用。趙亮醫(yī)生也告訴北京晨報(bào)記者，因?yàn)槎拘运幬镉懈髯缘乃幚碜饔?，目前不可?退出醫(yī)療市場。

關(guān)于預(yù)防兒童用藥不當(dāng)，冀連梅還介紹說，目前國內(nèi)通常是在藥品說明書中有所體現(xiàn)，在說明書的《注意事項(xiàng)》下提醒醫(yī)生和患者注意可能有耳毒性。

In the Chinese Disabled Persons Federation released "on the nineteenth national" love day "publicity and education activities of the notice" in the list of work items, referred to "screening for deafness genes" and "prevention and reduction of drug induced hearing disability occurred".

In Zhao Liang's view, genetic testing for the prevention of drug deafness is important, he said: "a part of drug-induced deafness related genes and, for the detection of deafness genes are found in the mitochondrial gene mutation in children, the more than ordinary children sensitive to the ototoxic drugs, should strictly control the use of."

For deafness gene screening, Hebei Lianmei said that at present China has been widely exist in the professional screening for neonatal deafness gene carriers, to determine whether a newborn with deafness gene aminoglycoside.

She forwarded to the Beijing morning news reporter gene screening of a patient has produced after the medication guide card, the card marked with this text: "I and the maternal family members of your life should be absoluy disabled or caution aminoglycoside antibiotic, then lists the streptomycin, kanamycin and other 10 kinds of antibiotics name."

Hebei Lianmei stressed gene screening, the doctor will give parents such a card, the above stated what drugs to disable or caution. Parents can show the card to the doctor when they take their children to see a doctor.

Ototoxic drugs not out of treatment

Pharmacists should strengthen the training and education

Drug deafness children despite the huge crowd, but Lianmei Hebei pharmacists pointed out that in the past that the improper use of drugs is one of the main causes of child deafness, big city now should not have this kind of problem, but at the grassroots level, drug abuse phenomenon is also very common." Hebei Lianmei said, now really still like gentamicin use at the grassroots level. Doctor Zhao Liang also told the Beijing morning news reporter, because of their pharmacological effects of ototoxic drugs, currently impossible to compley withdraw from the medical market.

On preventing children from inappropriate medication, Hebei Lianmei also said that at present is usually reflected in the drug instructions, the "notice" in the prospectus to remind doctors and patients to watch possible ototoxicity.